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. 2020 Dec 28;13:1178646920984163. doi: 10.1177/1178646920984163

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© The Author(s) 2020

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Immunohistochemical localization of indoleamine 2,3-dioxygenase at the maternal-fetal interface of human placenta. Immunostaining for indoleamine 2,3-dioxygenase-1 (IDO1), indoleamine 2,3-dioxygenase-2 (IDO2), cytokeratin 7 (CK7), CD68, rabbit-isotype control, and mouse-isotype control were performed. (A) Implantation site of 7 weeks of gestation. (B) Term chorionic villi and placental bed. (a) Lower magnification of the maternal-fetal interface. Scale bar: 300 µm. (b) Higher magnification of the same area of the specimens depicted in (a). Scale bar: 50 µm. The results presented are from a single representative experiment performed with one 7 weeks sample and 5 term placentas.

Abbreviations: bv, blood vessel; cct, chorionic cytotrophoblast; exvct, extravillous cytotrophoblast; ge, glandular epithelium; ma, placental macrophage; stb, syncytiotrophoblast.