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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Exp Neurol. 2020 Oct 13;335:113507. doi: 10.1016/j.expneurol.2020.113507

Figure 3: N-acetylcysteine (NAC) administration prior to delayed hypoxemia reduces neuronal loss but does not modulate microglia density.

Figure 3:

(A) Experimental schematic. (B) NeuN immunohistochemical staining of the ipsilateral hippocampus. (C) Iba1 immunohistochemical staining of the ipsilateral hippocampus. Scale bar 250 μm. Higher magnification of the pyramidal layer of CA3. Scale bar 100 μm. (D) Stereological quantification of NeuN positive cells in the pyramidal layer of CA3. F(2,27)= 47.63 P<0.0001, * P < 0.001. ANOVA followed by post hoc Tukey tests. (E) Lesion volume measurements 4 days after CCI. (F) Stereological quantification of Iba-1 positive cells in the CA3 region of the hippocampus. Controlled cortical impact (CCI).