Table 2.
Univariate and multivariate linear regression analysis for association with magnesium.
| Univariable | Multivariable | |||
|---|---|---|---|---|
| Correlation coefficient | p value | St. Beta | p value | |
| Demographics | ||||
| Age (years) | −0.07 | 0.328 | ||
| Diabetes duration (years) | 0.02 | 0.813 | ||
| Male gender (n) | 0.04 | 0.580 | ||
| BMI (kg/m2) | 0.04 | 0.581 | ||
| Current smoker (yes) | −0.08 | 0.306 | ||
| Systolic blood pressure (mmHg) | −0.03 | 0.674 | ||
| Diastolic blood pressure (mmHg) | −0.09 | 0.236 | ||
| Mode of insulin administration: MDI (n) | 0.01 | 0.940 | ||
| Mode of insulin administration: CSII (n) | −0.01 | 0.940 | ||
| Total insulin dose (IE)a | 0.45 | 0.014 | n too small | |
| Complications | ||||
| Microvascular complications | ||||
| Retinopathy (n) | 0.08 | 0.286 | ||
| Neuropathy (n) | −0.12 | 0.122 | ||
| Micro-albuminuria (n) | 0.03 | 0.712 | ||
| Macro-albuminuria (n) | 0.07 | 0.303 | ||
| Macrovascular events | ||||
| Angina pectoris (n) | 0.05 | 0.507 | ||
| MI (n) | 0.12 | 0.099 | ||
| PTCA (n) | −0.05 | 0.449 | ||
| PAD (n) | 0.03 | 0.663 | ||
| CABG (n) | −0.12 | 0.081 | −0.103 | 0.142 |
| TIA (n) | 0.04 | 0.589 | ||
| CVA (n) | 0.03 | 0.629 | ||
| Laboratory measurements | ||||
| HbA1c (%) | −0.01 | 0.843 | −0.094 | 0.195 |
| HbA1c (mmol/mol) | −0.01 | 0.843 | ||
| Creatinine (µmol/l) | 0.08 | 0.276 | 0.104b | 0.148 |
| eGFR (MDRD, ml/min/1.73 m2) | 0.11 | 0.110 | ||
| Total cholesterol (mmol/l) | 0.08 | 0.272 | 0.154 | 0.766 |
| HDL cholesterol (mmol/l) | −0.10 | 0.165 | −0.154 | 0.514 |
| Total cholesterol:HDL ratio | 0.12 | 0.084 | ||
| LDL cholesterol (mmol/l) | 0.11 | 0.118 | −0.042 | 0.927 |
| Triglycerides (mmol/l) | 0.05 | 0.503 | −0.094b | 0.612 |
| C-reactive protein (mg/l) | −0.05 | 0.516 | ||
| R–SH (µM) | −0.06 | 0.416 | –0.213 | 0.007 |
| NT-proBNP (pmol/l) | −0.01 | 0.886 | ||
| Calcium (mmol/l) | 0.08 | 0.230 | ||
| Albumin (g/l) | 0.19 | 0.007 | 0.298 | 0.000 |
| Phosphate (mmol/l) | 0.06 | 0.412 | ||
| PTH (pmol/l) | 0.01 | 0.930 | ||
| 25-OH Vitamin D (ng/ml) | −0.05 | 0.462 | ||
Adjusted R² for the multivariable model: 0.075; F (9, 189) = 2.79, p = 0.004.
n = 29.
St.Beta of the ln-transformed parameter.
BMI, body mass index; CABG, coronary artery bypass grafting; CSII, continuous subcutaneous insulin infusion; CVA, cerebral vascular event; eGFR, estimated glomerular filtration rate; HbA1c, glycated haemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MDI, multiple daily injections; MDRD, modification of diet in renal disease; MI, myocardial infarction; NT-proBNP, N-terminal pro-B type natriuretic peptide; PTCA, percutaneous transluminal coronary angioplasty; PTH; parathyroid hormone; R–SH, total free thiol groups; TIA, transient ischemic attack.