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HFCD diet exerts gut dysbiosis. Mice were fed a control (n = 5 for each time point) or HFCD diet (n = 8–10 for each time point) for 14 and 24 weeks. Luminal samples of small intestine and cecum were collected as described in Materials and methods section. The influence of HFCD diet on the composition of the small intestine (A) and cecum (B) gut microbiota was assessed by PCoA. Data represent mean values ± SEM for four individual mice.
