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. 2020 Sep 24;143(10):2945–2956. doi: 10.1093/brain/awaa242

Table 1.

Pathways detected in the visual cortex brown module that was over-represented for mutations

Module Mutated genes Pathways P-value
VC brown 197 Thyrotropin-releasing hormone receptor signalling pathway 0.046
Oxytocin receptor mediated signalling pathway 0.045
Alzheimer’s disease-amyloid secretase pathway 0.040
5HT2 type receptor mediated signalling pathway 0.040
Heterotrimeric G-protein signalling pathway-Gq alpha and Go alpha mediated pathway 0.017

Number of mutated genes in families is listed as well as corrected P-values.