Table 1.
Module | Mutated genes | Pathways | P-value |
---|---|---|---|
VC brown | 197 | Thyrotropin-releasing hormone receptor signalling pathway | 0.046 |
Oxytocin receptor mediated signalling pathway | 0.045 | ||
Alzheimer’s disease-amyloid secretase pathway | 0.040 | ||
5HT2 type receptor mediated signalling pathway | 0.040 | ||
Heterotrimeric G-protein signalling pathway-Gq alpha and Go alpha mediated pathway | 0.017 |
Number of mutated genes in families is listed as well as corrected P-values.