Table 1.
The clinical characteristics of the included patients.
| Items | CHB | LC | Early-stage CHB-HCC | Early-stage LC-HCC | P |
|---|---|---|---|---|---|
| N | 48 | 64 | 33 | 55 | |
| Sex | |||||
| Male | 35 | 42 | 25 | 45 | 0.252 |
| Female | 13 | 22 | 8 | 10 | |
| Age (years) | |||||
| ≤50 | 30 | 55 | 24 | 35 | 0.017* |
| >50 | 18 | 9 | 9 | 20 | |
| Child–Pugh | |||||
| A | 48 | 47 | 30 | 45 | 0.001* |
| B | 0 | 14 | 3 | 9 | |
| C | 0 | 3 | 0 | 1 | |
| AST (U/L) | |||||
| ≤40 | 37 | 48 | 24 | 43 | 0.940 |
| >40 | 11 | 16 | 9 | 12 | |
| ALT (U/L) | |||||
| ≤50 | 42 | 61 | 25 | 42 | 0.003* |
| >50 | 6 | 3 | 8 | 13 | |
| TBil (µmol/L) | |||||
| ≤21 | 40 | 33 | 23 | 41 | 0.002* |
| >21 | 8 | 31 | 10 | 14 | |
| AFP (ng/mL), median (interquartile range) | 2.47 (1.54, 2.99) | 2.82 (1.70, 4.76) | 8.80 (3.24, 214.1) | 19.46 (3.21, 194.5) | |
| DCP (mAU/mL), median (interquartile range) | 23 (18, 27.75) | 26 (16, 32) | 36 (22.5, 2586) | 34 (17.5,114.3) | < |
Data are presented as numbers unless otherwise indicated.
*, P < 0.05.
CHB, chronic hepatitis B virus infection; LC, liver cirrhosis; HCC, hepatocellular carcinoma; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TBil, total bilirubin; AFP, alpha-fetoprotein; DCP, des-gamma-carboxyprothrombin.