Table 2.
Z-score distribution and percentage of echocardiograms with Z-scores ≥ 2.5 in Boston and PHN models
| Acute phase (echocardiograms, N = 345) | Boston | PHN | CCC/κ (95% CI)* |
|---|---|---|---|
| LAD z-score (N = 344) Median (IQR) | 0.7 (− 0.4, 2.1) | 2.0 (0.9, 3.4) | 0.92 (0.91, 0.93) |
| LAD z-score ≥ 2.5 | 70 (20.3%) | 145 (42.2%) | 0.52 (0.43, 0.60) |
| RCA z-score (N = 344) Median (IQR) | 0.9 (0.0, 1.7) | 0.7 (0.0, 1.4) | 0.97 (0.97, 0.97) |
| RCA z-score ≥ 2.5 | 54 (15.7%) | 36 (10.5%) | 0.77 (0.67, 0.87) |
| LMCA z-score (N = 342) Median (IQR) | 0.6 (− 0.3, 1.3) | 0.5 (− 0.2, 1.2) | 0.99 (0.99, 0.99) |
| LMCA z-score ≥ 2.5 | 23 (6.7%) | 16 (4.7%) | 0.81 (0.71, 0.91) |
| Subacute phase (echocardiograms, N = 286) | |||
|---|---|---|---|
| LAD z-score (N = 284) Median (IQR) | 0.3 (− 0.6, 1.4) | 1.6 (0.7, 2.7) | 0.96 (0.95, 0.96) |
| LAD z-score ≥ 2.5 | 42 (14.8%) | 85 (29.9%) | 0.58 (0.47, 0.68) |
| RCA z-score (N = 284) Median (IQR) | 0.5 (− 0.3, 1.4) | 0.4 (− 0.2, 1.1) | 0.98 (0.97, 0.98) |
| RCA z-score ≥ 2.5 | 34 (12%) | 28 (9.9%) | 0.89 (0.81, 0.98) |
| LMCA z-score (N = 284) Median (IQR) | 0.3 (− 0.4, 1.1) | 0.3 (− 0.3, 1.0) | 0.99 (0.99, 0.99) |
| LMCA z-score ≥ 2.5 | 21 (7.4%) | 17 (6%) | 0.83 (0.74, 0.93) |
| Convalescent phase (echocardiograms, N = 273) | |||
|---|---|---|---|
| LAD z-score (N = 268) Median (IQR) | − 0.1 (− 0.9, 0.9) | 1.2 (0.4, 2.2) | 0.96 (0.95, 0.96) |
| LAD z-score ≥ 2.5 | 19 (7.1%) | 58 (21.6%) | 0.43 (0.3, 0.57) |
| RCA z-score (N = 271) Median (IQR) | 0.2 (− 0.5, 1.1) | 0.2 (− 0.3, 0.8) | 0.97 (0.97, 0.97) |
| RCA z-score ≥ 2.5 | 20 (7.4%) | 15 (5.5%) | 0.85 (0.72, 0.98) |
| LMCA z-score (N = 271) Median (IQR) | 0.1 (− 0.7, 0.8) | 0.1 (− 0.6, 0.7) | 0.99 (0.99, 0.99) |
| LMCA z-score ≥ 2.5 | 11 (4.1%) | 11 (4.1%) | 0.81 (0.68, 0.94) |
| All illness phases (total echocardiograms, N = 904) | Boston | PHN | CCC/κ (95% CI) |
|---|---|---|---|
| LAD z-score (N = 896) Median (IQR) | 0.3 (− 0.6, 1.5) | 1.6 (0.7, 2.8) | 0.94 (0.93, 0.95) |
| LAD z-score ≥ 2.5 | 131 (14.6%) | 288 (32.1%) | 0.53 (0.46, 0.60) |
| RCA z-score (N = 899) Median (IQR) | 0.5 (− 0.3, 1.5) | 0.4 (− 0.2, 1.1) | 0.97 (0.97, 0.98) |
| RCA z-score ≥ 2.5 | 108 (12.0%) | 79 (8.8%) | 0.83 (0.77, 0.89) |
| LMCA z-score (N = 897) Median (IQR) | 0.3 (− 0.4, 1.1) | 0.3 (− 0.4, 1.0) | 0.99 (0.99, 0.99) |
| LMCA z-score ≥ 2.5 | 55 (6.1%) | 44 (4.9%) | 0.82 (0.73, 0.90) |
*Lin’s Concordance Correlation Coefficient (CCC) is used for continuous variables, κ for dichotomous variables. Interpretation of CCC: CCC 95% CI with lower limit value: < 0.90 = poor agreement; 0.90 to < 0.95 = moderate; 0.95 to 0.99 = substantial; > 0.99 = nearly perfect agreement [9]. Interpretation of κ: κ 95% CI with lower limit: value < 0 = no agreement; 0.00–0.21 = slight agreement; 0.21–0.40 = fair agreement; 0.41–0.60 = moderate agreement; 0.61–0.80 = substantial agreement; 0.81–0.99 = almost perfect agreement; 1.0 = perfect agreement [10]