Fig. 5.

CircNOL10-mediated suppressive effects on BC cell malignant behaviors are reversed by miR-767-5p up-regulation. a–d BT-549 and MDA-MB-231 cells were transfected with miR-NC, miR-767-5p, miR-NC + circNOL10 or miR-767-5p + circNOL10. a Plate clonality assays were used to monitor the colony forming ability. b, c Transwell assays were performed to examine cell migration and invasion. d Western blot assays were applied to determine the protein expression of EMT-related genes including E-cadherin, N-cadherin and vimentin.*P < 0.05, **P < 0.01, ***P < 0.001