Table III.

FSSG scores in patients with systemic sclerosis-related GERD before and after vonoprazan treatment.

FSSG score	Before vonoprazan	After vonoprazanc	Mean improvement rated ± SD	P-valuee
Total score, mean (SD)	25.2 (10.7)	9.6 (7.0)	60.8%±21.2	0.0004b
Acid reflux score, mean (SD)	14.1 (6.6)	4.6 (5.1)	67.3%±24.8	<0.0001b
Dysmotility score, mean (SD)	11.1 (4.6)	4.8 (3.5)	55.4%±26.0	0.0022a

^aP<0.05,

^bP<0.001.

^cVonoprazan dose, 10 or 20 mg/day.

^dImprovement rate=(before vonoprazan score-after vonoprazan treatment score)/before vonoprazan score x100 (%). The duration of observation was 4-28 weeks after vonoprazan treatment.

^eA Wilcoxon paired test was used. GERD, gastroesophageal reflux disease; FSSG, frequency score for symptoms of GERD; SD, standard deviation.