Table 6. Genotype and allele frequency results of rs2305948 before and after adjustment of (BMI, sex, age, HT, DM, and Smoking).
| rs2305948 (C/T) |
Control N=213 |
CR N=111 |
Unadjusted OR. |
Unadjusted (95%CI) |
P-value | Adjusted OR. |
Adjusted (95%CI) |
P-value |
|---|---|---|---|---|---|---|---|---|
| Co-dominant | ||||||||
| CC (Ref.) | 173 | 66 | ||||||
| CT | 36 | 38 | 2.76 | 1.61-4.73 | 0.000 | 3.13 | 1.76-5.57 | 0.000 |
| TT | 4 | 7 | 4.58 | 1.30-16.18 | 0.01 | 5.4 | 1.49-19.59 | 0.01 |
| Dominant | ||||||||
| TT+CT vs. CC | 40 | 45 | 2.86 | 1.71-4.76 | 0.000 | 3.28 | 1.90-5.68 | 0.000 |
| Recessive | ||||||||
| CC+CT (Ref.) | 209 | 104 | ||||||
| TT | 4 | 7 | 3.5 | 1.002-12.22 | 0.05 | 3.83 | 1.08-13.16 | 0.03 |
| Additive | ||||||||
| 2(TT)+CT | 44 | 52 | 3.09 | 1.89-5.06 | 0.0001 | |||
| MAF (T) | 10.32 | 23.42 | 3.51 | 1.006-12.28 | 0.04 | |||