Table 3.

Sensitivity analyses.

	Odds ratios and 95% confidence intervals
	Lifetime depression (excluding PND)	Lifetime severe depression	Current depression	Current severe depression	Lifetime depression
	n = 50 143	n = 38 990	n = 40 727	n = 40 551	n = 52 078
	Yes: 13 953 No: 36 190	Yes: 2 333 No: 36 657	Yes: 896 No: 39 831	Yes: 720 No: 39 831	Yes: 15 421 No: 36 657
Cohabitation status (living with spouse/partner)
No	Ref	Ref	Ref	Ref	Ref
Yes	0.67*** (0.61, 0.74)	0.60*** (0.50, 0.72)	0.58*** (0.45, 0.76)	0.65** (0.49, 0.89)	0.67*** (0.62, 0.74)
Number of children
Childless	Ref	Ref	Ref	Ref	Ref
Parent of 1	1.10* (1.01, 1.20)	1.28** (1.06, 1.54)	1.45* (1.09, 1.92)	1.55** (1.13, 2.13)	1.17*** (1.07, 1.27)
Parent of 2	0.94 (0.88, 1.01)	1.13 (0.97, 1.31)	1.10 (0.87, 1.40)	1.11 (0.85, 1.46)	1.01 (0.95, 1.08)
Parent of 3	1.02 (0.94, 1.10)	1.26* (1.05, 1.51)	1.18 (0.88, 1.57)	1.23 (0.89, 1.70)	1.11* (1.03, 1.20)
Parent of 4+	1.15* (1.02, 1.28)	1.76*** (1.38, 2.23)	1.85** (1.27, 2.68)	2.10*** (1.39, 3.15)	1.27*** (1.14, 1.42)

Note: PND = postnatal depression. All analyses were conducted using the full model that included cohabitation status and number of children, adjusted for age, sex, marital separation/divorce (in the two years prior to assessment), death of spouse/partner (in the two years prior to assessment), migrant status, highest educational/professional qualification, annual gross household income, employment status, Townsend deprivation index, smoking status, alcohol use, neuroticism, long-standing illness, disability or infirmity, traumatic life events, adverse childhood experiences, participation in social/leisure activities, loneliness, ever had same-sex intercourse, lifetime number of sexual partners, body mass index, depression polygenic risk score, six ancestry-informative principal components, batch number and assessment centre. *** p < 0.001, ** p < 0.01, * p < 0.05 (corrected for multiple testing at 5% false discovery rate).