Table 3.

Clinical pathological parameters of patients with soft-tissue sarcoma with or without mutations and CNVs of m⁶A regulatory genes.

		With mutation and/or CNV*	Without mutation and CNV*	P
Sex	Female	105	7	0.313
	Male	84	10
Age	≤60	93	11	0.312
	>60	96	6
Histologic diagnosis	DDLPS	40	10	<0.001
	UPS	43	1
	MFS	17	0
	LMS	79	1
	MPNST	4	1
	SS	6	4
Metastatic	YES	45	1	0.264
	NO	82	7
	N/A**	62	9
Tumor size (cm)	≥12.7***	69	11	0.040
	<12.7	112	6
	N/A**	8	0
FNCLCC grade	1	13	1	0.322
	2	100	12
	3	76	4

N/A – not applicable.

^*With mutation and/or copy number variation (CNV): The Cancer Genome Atlas (TCGA) soft tissue sarcoma patients with mutant or CNV or mutant + CNV; Without mutation and CNV: TCGA soft tissue sarcoma patients with neither mutant nor CNV;

^**ambiguous variables (N/A) were excluded from chi-square test or Fisher exact test;

^***the average of tumor size is 12.7 cm.