Table 2.
Correlation of Demographic, Clinical, Biochemical and Urinary Markers with eGFR and ACR in Type 2 Diabetic Patients
eGFR | ACR | |||
---|---|---|---|---|
r | p | r | p | |
Age, years | −0.088 | 0.236 | 0.078 | 0.295 |
Sex, male | −0.166 | 0.024 | −0.049 | 0.506 |
BMI, kg/m2 | −0.174 | 0.019 | 0.029 | 0.696 |
Duration of diabetes, years | −0.097 | 0.190 | 0.168 | 0.023 |
SBP, mmHg | −0.308 | <0.001 | 0.339 | <0.001 |
DBP, mmHg | −0.003 | 0.966 | 0.005 | 0.948 |
FBG, mg/dL | −0.098 | 0.192 | 0.334 | <0.001 |
HbA1c, % | −0.071 | 0.337 | 0.275 | <0.001 |
ACR, mg/g | −0.616 | <0.001 | – | – |
eGFR, mL/min/1.73 m2 | – | – | −0.616 | <0.001 |
Total protein/Cr, mg/g | −0.504 | <0.001 | 0.779 | <0.001 |
Transferrin/Cr, µg/g | −0.408 | <0.001 | 0.679 | <0.001 |
RBP/Cr, µg/g | −0.348 | <0.001 | 0.492 | <0.001 |
NGAL/Cr µg/g | −0.328 | <0.001 | 0.392 | <0.001 |
KIM-1/Cr, µg/g | −0.198 | 0.007 | 0.012 | 0.867 |
MCP-1/Cr, µg/g | −0.281 | <0.001 | 0.394 | <0.001 |
Note: p < 0.05 was considered significant.
Abbreviations: eGFR, estimated glomerular filtration rate; ACR, albumin-to-creatinine ratio; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBG, fasting blood glucose; HbA1c, hemoglobin A1c; total protein/Cr, total protein-to-creatinine ratio; transferrin/Cr, transferrin-to-creatinine ratio; RBP/Cr, retinol-binding protein-to-creatinine ratio; NGAL/Cr, neutrophil gelatinase-associated lipocalin-to-creatinine ratio; KIM-1/Cr, kidney injury molecule 1-to-creatinine ratio; MCP-1/Cr, monocyte chemoattractant protein 1-to-creatinine ratio; r, coefficients of correlation.