Table 3.

Multiple Linear Regression Analysis of Urinary Markers with eGFR as Dependent Variable

Model	Total Protein/Cr		Transferrin/Cr		RBP/Cr		NGAL/Cr		KIM-1/Cr		MCP-1/Cr
	Standard β	p	Standard β	p	Standard β	p	Standard β	p	Standard β	p	Standard β	p
1	−0.585	<0.001	−0.416	<0.001	−0.456	<0.001	−0.424	<0.001	−0.180	0.016	−0.442	<0.001
2	−0.568	<0.001	−0.413	<0.001	−0.451	<0.001	−0.420	<0.001	−0.152	0.057	−0.443	<0.001
3	−0.558	<0.001	−0.409	<0.001	−0.439	<0.001	−0.409	<0.001	−0.184	0.020	−0.429	<0.001
4	−0.332	0.001	0.011	0.885	−0.176	0.007	−0.165	0.011	−0.088	0.154	−0.150	0.023

Notes: Logarithm-transformed values of eGFR, ACR and urinary markers were used for analysis. Model 1, crude. Model 2, adjusted for age, sex, and duration of diabetes. Model 3, adjusted for age, sex, duration of diabetes, FBG, hypertension, hyperlipidemia. Model 4, adjusted for age, sex, duration of diabetes, FBG, hypertension, hyperlipidemia, ACR. Values of p < 0.05 were considered significant.

Abbreviations: RBP/Cr, retinol-binding protein-to-creatinine ratio; NGAL/Cr, neutrophil gelatinase-associated lipocalin-to-creatinine ratio; KIM-1/Cr, kidney injury molecule 1-to-creatinine ratio; MCP-1/Cr, monocyte chemoattractant protein 1-to-creatinine ratio; Total protein/Cr; total protein-to-creatinine ratio; transferrin/Cr transferrin-to-creatinine ratio.