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. 2021 Jan;64(1):126–137. doi: 10.1165/rcmb.2020-0164OC

Figure 5.

Figure 5.

NELF protein-level changes in response to LAIV inoculation. NELF was analyzed for changes in nasal protein levels induced by LAIV by using the AUCs of levels at baseline (D0), D1, D2, and D8. The AUCs for (A) MCP-1, (B) MIP-1β, (C) MIP-1α, (D) IL-6, (E) IL12p40, (F) IFNγ, (G) IL-1α, (H) IL-2, and (I) VEGF are shown. Cigarette smoke–induced increases are shown in A–C, e-cigarette–suppressed responses are shown in D–F, and e-cigarette–induced increases are shown in G–I. Data are shown as the mean ± SEM. *P ≤ 0.1, **P ≤ 0.05, and ***P ≤ 0.01 compared with nonsmokers. MCP-1 = monocyte chemoattractant protein-1; MIP-1 = macrophage inflammatory protein-1; VEGF = vascular endothelial growth factor.