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. 2020 Dec 31;12:13513–13525. doi: 10.2147/CMAR.S272287

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© 2020 Yue et al.

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Circ_101341 was highly expressed in ccRCC tissues and cells. (A) The differential expression of several circRNAs in ccRCC tissues identified from the GSE100186 dataset was shown in the heat map. (B) Schematic diagram illustrated that circ_101341 was generated from EGLN3 pre-mRNA. (C) Circ_101341 was highly expressed in ccRCC from the GSE100186 dataset. (D) The expression of circ_101341 in ccRCC tissues (n=60) and normal tissues (n=60) was measured by qRT-PCR. (E) The overall survival curve was generated by Kaplan–Meier plot and analyzed by Log rank test. (F) The expression of circ_101341 in ccRCC cell lines (SW839, A498, Caki-1 and 786-O) was detected by qRT-PCR. (G) The circularity and stability of circ_101341 were detected using RNase R by qRT-PCR. *P < 0.05.