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. 2020 Dec 31;12:13513–13525. doi: 10.2147/CMAR.S272287

Figure 2.

Figure 2

Circ_101341 knockdown inhibited proliferation and colony formation in vitro and repressed tumor growth in vivo. A498 and SW839 cells were transfected with sh-circ to observe the role of circ_101341. (A and B) The transfection efficiency was checked using qRT-PCR. (C and D) Cell proliferation was assessed by CCK-8 assay. (E) The ability of cell proliferation was monitored by colony formation assay. (F and G) The animal experiment was conducted to assess the role of circ_101341 knockdown in tumor growth (tumor volume and weight). *P < 0.05.