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. 2020 Dec 31;15:3407–3416. doi: 10.2147/COPD.S278553

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© 2020 Liu et al.

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The expression level of miR-218 in chronic obstructive pulmonary disease. (A and B) Forced expiratory volume in one second (FEV1) % index and the relative level of miR-218 were displayed in non-smokers, smokers and COPD tissues. (C) The correlation relationship between FEV1% index and miR-218 level was analyzed in COPD patients by Pearson’s correlation analysis. (D–F) Pearson’s correlation analysis was used to analyze the correlation relationship between miR-218 and serum IL-6, IL-8, and TNF-α levels. Data are shown as mean ± SD from three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001.

Abbreviations: FEV1, Forced expiratory volume in one second; COPD, chronic obstructive pulmonary disease; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; IL-6, interleukin-6.