Table 2.

Unadjusted and Adjusted Linear Regression Models for the Association Between iGFR, eGFR, and TFV-DP-DBS (for Every 500-fmol/Punch)

Models	TFV-DP-DBS $\widehat{\beta }$ (95% CI)	P Value
iGFR
Unadjusted Model	0.04 (−3.34 to 3.41)	.98
Age Adjusted	0.08 (−2.63 to 2.79)	.95
BMI Adjusted	−1.23 (−4.33 to 1.86)	.42
Total Fat Mass Adjusted	−1.01 (−3.97 to 1.94)	.49
LBM Adjusted	0.09 (−3.38 to 3.57)	.96
Appendicular Lean Mass Adjusted	0.19 (−3.27 to 3.64)	.91
Age and BMI Adjusted	−0.55 (−3.35 to 2.25)	.69
Age and Total Fat Mass Adjusted	−0.52 (−3.21 to 2.16)	.69
eGFRa
Unadjusted Model	−2.63 (−6.22 to 0.95)	.15
Age Adjusted	−2.10 (−5.47 to 1.27)	.22
BMI Adjusted	−3.06 (−6.78 to 0.67)	.11
Total Fat Mass Adjusted	−2.81 (−6.53 to 0.92)	.14
LBM Adjusted	−2.46 (−6.12 to 1.21)	.18
Appendicular Lean Mass Adjusted	−2.39 (−6.02 to 1.24)	.19
Age and BMI Adjusted	−1.92 (−5.55 to 1.71)	.29
Age and Total Fat Mass Adjusted	−1.74 (−5.30 to 1.82)	.33

Abbreviations: BMI, body mass index; CI, confidence interval; eGFR, estimated glomerular filtration rate; DBS, dried blood spots; iGFR, iohexol glomerular filtration rate; LBM, lean body mass; TFV-DP, tenofovir-diphosphate.

^aeGFR by the Modification of Diet in Renal Disease equation.