Table 2.
Insulin type | Time of onset | Duration | Peak effect |
---|---|---|---|
Rapid-acting | |||
Lispro | 10-30 min | 3-5 h | 30-60 min |
Aspart | 10-30 min | 3-5 h | 30-60 min |
Glulisine | 10-30 min | 3-5 h | 2 h |
Short-acting | |||
Regular human insulin | 30-60 min | 5-12 h | 1.5-2 h |
Intermediate-acting | |||
NPH, Lente | 1-2 h | 10-20 h | 4-8 h |
Long-acting | |||
Ultralente | 2-4 h | 16-24 h | 8-20 h |
Glargine | Up to 6 h | Up to 24 h | No peak |
Detemir | 2-4 h | 20 h | No peak |
Degludec | 0.5-1.5 h | Up to 48 h | No peak |
Gla-300 | Up to 6 h | Up to 36 h | No peak |
Source: McKenna.[25] NPH – Neutral protamine Hagedorn