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[Preprint]. 2020 Dec 31:rs.3.rs-132821. [Version 1] doi: 10.21203/rs.3.rs-132821/v1

Figure 3. SARS-CoV-2 infection elicits a robust memory B cell response.

Figure 3.

a) Example plots of influenza virus hemagglutinin (HA) and S staining on IgDlo CD20+ CD38lo/int CD19+ CD3− live singlet lymphocytes (gating in Extended Data Fig. 1a) from control (left) and convalescent (right) PBMC 7 months after symptom onset. b) Frequencies of influenza virus HA- (left) and S- (right) binding memory B cells in PBMC from control (closed circles) and convalescent (open circles) participants 7 months after symptom onset. The dotted line in the S plot indicates limit of sensitivity, defined as the median + 2× SD of the controls. Each symbol represents one sample (n=18 convalescent, 11 control). Horizontal lines indicate medians. P-values from two-sided Mann-Whitney U-tests.