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[Preprint]. 2020 Dec 29:2020.12.05.20241927. [Version 3] doi: 10.1101/2020.12.05.20241927

Figure 7: Neutralization potency of a panel of monoclonal antibodies targeting the RBD is not impacted by Spike mutations.

Figure 7:

Lentivirus pseudotyped with SARS-CoV-2 Spike protein: WT (D614G background), D796H, ΔH69/V70, D796H+ΔH69/V70 were produced in 293T cells and used to infect target Hela cells stably expressing ACE2 in the presence of serial dilutions of indicated monoclonal antibodies. Data are representative of at least two independent experiments. RBD: receptor binding domain. Classes of RBD binding antibodies are indicated based Bouwer et al.