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. 2020 Dec 31;13:13315–13327. doi: 10.2147/OTT.S262408

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© 2020 Li et al.

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Circ_0001175 promoted HCC cell proliferation, migration and invasion (A). Circ_0001175 was overexpressed in Huh-7 cells, and it was knocked down in SMMC-7721 cells. qRT-PCR was used to validate the transfection efficiency. (B and C) CCK-8 and BrdU assays were used to detect the function of circ_0001175 in regulating the proliferation of HCC cells. (D) The function of circ_0001175 in regulating HCC cell migration and invasion was examined using Transwell assay. *P < 0.05, **P < 0.01 and ***P < 0.001.