Figure 5.

Circ_0001175 promoted proliferation, migration and invasion of HCC cells by adsorbing miR-130a-5p. (A) Huh-7 cells were co-transfected with circ_0001175 overexpression plasmid+miR-130a-5p mimics, and SMCC-7721 cells were co-transfected with circ_0001175 siRNA+miR-130a-5p inhibitors. qRT-PCR was then used to detect expression of miR-130a-5p after co-transfection was performed in HCC cells. (B- D) CCK-8, BrdU and Transwell assays were used to detect the proliferation, migration and invasion of HCC cells after transfection. *P < 0.05, **P < 0.01 and ***P < 0.001. In (B) ^#P < 0.01, vs circ_0001175 overexpression group or knockdown group.