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. 2021 Jan 4;16(1):e0243774. doi: 10.1371/journal.pone.0243774

Table 2. Results of the incidence trend analysis of Inflammatory Bowel Disease (IBD), Crohn’s Disease (CD), Ulcerative Colitis (UC) and unclassified IBD (IBD-U) for all patients and separately by gender using joinpoint regression.

disease gender APC % APC 95% CI p-value trend
IBD all + 6.3 [ 0.4–12.6] 0.040 significant increase
IBD male + 7.3 [ 0.1–14.9] 0.047 significant increase
IBD female + 5.5 [– 1.5–13.0] 0.108 n.s.
CD all + 5.4 [– 1.9–13.3] 0.129 n.s.
CD male + 5.6 [– 3.1–15.1] 0.180 n.s.
CD female + 5.6 [– 4.1–16.2] 0.227 n.s.
UC all + 6.3 [ 0.1–12.8] 0.046 significant increase
UC male + 8.1 [– 1.3–18.3] 0.084 n.s.
UC female + 3.1 [– 7.7–15.2] 0.538 n.s.
IBD-U all no estimate is possible due to zero values in the installments

n.s. = not significant, APC = annual percent change