Figure 3.

Representative examples of bioactivity in different cell types. (A), fluorescent (calcein) staining ($\text{objective magnification}=20\times$) of untreated (control) iCell neurons or cell treated with vehicle, or two designed mixtures (${\text{AC}}_{50}\text{-H}$ at lowest tested concentration, diluted by $\mathrm{10,000}\times$ from the highest concentration, and POD-H at an intermediate tested concentration, diluted by $100\times$ from the highest concentration). See acronym explanations and description of the designed mixtures in Table 1. (B), characteristic kinetic imaging-derived fluorescence intensity traces indicative of the ${\mathrm{Ca}}^{2+}$ fluxes across cell membranes of iCell cardiomyocytes that spontaneously contract in cell culture. (C), fluorescent (calcein) staining ($\text{objective magnification}=4\times$) of untreated (control) HUVECs or cell treated with vehicle, or two designed mixtures. See Table 1 for description of designed mixtures ${\text{AC}}_{50}\text{-H}$ and POD-H.