Figure 4.

Representative Bayesian curve-fitting examples of concentration–response profiles for individual chemicals (insets) and a representative designed mixture (${\text{AC}}_{50}\text{-H}$; see Table 1 for description) for total outgrowth in iCell neurons (results for all other phenotypes can be found in Supplemental Materials Figures S1–S94 and a Supplemental Excel file). See acronym explanations and description of the designed mixtures in Table 1. Dots represent experimental data points. Gray lines represent individual simulated curves from the last 100 iterations. The vertical dashed red lines represent the 90% credible interval on the point of departure (${\text{EC}}_{10}$).