Table 5.
Patient-Reported Outcomes and Sleep Apneaa
| PWH (n = 321) | HIV-negative (n = 118) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Outcome | SA (n = 20) | No SA (n = 301) | Adjusted differenceb (95% CI) | P | SA (n = 9) | No SA (n = 109) | Adjusted differenceb (95% CI) | P | P for interaction |
| SF-36 Physical Component Score | 50.8 (39.7, 53.4) | 51.3 (41.5, 56.3) | –1.4 (-8.8 to 6.1) | .72 | 53.5 (41.0, 56.3) | 55.3 (52.6, 57.8) | –2.9 (–7.3 to 1.5) | .19 | .97 |
| SF-36 Mental Component Score | 41.6 (35.6, 57.0) | 50.9 (40.5, 56.5) | –9.2 (–17.3 to –1.0) | .03 | 53.7 (45.2, 55.5) | 54.8 (49.6, 58.4) | –2.4 (–9.6 to 4.9) | .52 | .28 |
| PROMIS Sleep Disturbance Score | 51.2 (43.5, 57.3) | 52.2 (45.5, 57.3) | 0.0 (-5.4 to 5.4) | 1.00 | 52.2 (44.2, 53.3) | 47.9 (42.9, 53.3) | 3.1 (–4.6 to 10.8) | .42 | .33 |
| PROMIS Sleep- Related Impairment Score | 52.3 (43.6, 61.3) | 50.3 (45.5, 57.2) | 1.2 (–4.5 to 6.9) | .68 | 45.5 (41.4, 55.1) | 45.5 (41.4, 50.3) | 1.4 (–5.8 to 8.7) | .69 | .98 |
Abbreviations: CI, confidence interval; HIV, human immunodeficiency virus, PROMIS, Patient-Reported Outcomes Measurement Information System; PWH, persons with HIV; SA, sleep apnea; SF-36, 36-item Short Form.
aAssociation of sleep apnea with patient-reported outcomes, stratified by HIV status and with P value tests for interactions by HIV status. Group values are shown as median (interquartile range) and differences as adjusted difference (95% CI). For SF-36 Physical Component and Mental Component Scores, lower scores indicate worse health-related quality of life. For patient-reported outcomes Measurement Information System (PROMIS) questionnaires for sleep disturbance and sleep-related impairment, higher scores indicate worse health-related quality of life.
bAdjusted for age, sex, and ethnicity.