Figure 2.

A, B, In lungs of B6 mice, Cp1038 spherules, stained dark red or brown, are sparse in lesions on days 5 (A) and 7 (B) after infection and are approximately 10–15 µm in diameter. C, On day 14 after infection, the abundance of spherules is modestly increased, and some spherules reach a diameter of approximately 20 µm (A–C, PRA stain, original magnification ×200; scale bars = 20 µm). D, For comparison, a B6 mouse from a study infected with 50 arthroconidia of Silveira had large, floridly abundant spherules on day 14 after infection (PRA stain, original magnification ×100; scale bar = 50 µm).