Table 1:
Tumour and treatment characteristics of patients with textbook outcomes after surgery for non-small-cell lung cancer
| Textbook outcome | No textbook outcome | P-valuea | |
|---|---|---|---|
| (n = 1430), n (%) | (n = 4083), n (%) | ||
| Sex | |||
| Male | 720 (50.3) | 2339 (57.3) | <0.001 |
| Female | 710 (49.7) | 1744 (42.7) | |
| Age (years) | |||
| 20–59 | 329 (23) | 791 (19.4) | 0.003 |
| 60–69 | 561 (39.2) | 1573 (38.5) | |
| 70–79 | 472 (33) | 1459 (35.7) | |
| >80 | 68 (4.8) | 260 (6.4) | |
| ASA group | |||
| I–II | 1120 (78.3) | 3015 (73.8) | <0.001 |
| III–IV | 888 (21.7) | 1068 (26.2) | |
| Charlson score | |||
| 0 | 500 (35) | 1290 (31.6) | 0.055 |
| 1 | 412 (28.8) | 1207 (29.6) | |
| 2+ | 518 (36.2) | 1586 (38.8) | |
| Cardiac comorbidity | |||
| No | 1087 (76) | 2939 (72.0) | 0.003 |
| Yes | 343 (24) | 1144 (28) | |
| Pulmonary comorbidity | |||
| No | 989 (69.2) | 2525 (61.8) | <0.001 |
| Yes | 441 (30.8) | 1558 (38.2) | |
| Diabetes mellitus | |||
| No | 1252 (87.6) | 3533 (86.5) | 0.33 |
| Yes | 178 (1.4) | 550 (13.5) | |
| Neurological comorbidity | |||
| No | 1223 (85.5) | 3478 (85.2) | 0.099 |
| Yes | 207 (14.5) | 605 (14.8) | |
| Thrombotic comorbidity | |||
| No | 1382 (96.6) | 3950 (96.7) | 0.74 |
| Yes | 48 (3.4) | 133 (3.3) | |
| Vascular comorbidity | |||
| No | 908 (63.5) | 2490 (61) | 0.097 |
| Yes | 522 (36.5) | 1593 (39) | |
| DLCO | |||
| >40% | 700 (49) | 2076 (50.8) | <0.001 |
| <40% | 14 (1) | 69 (1.7) | |
| Missing | 716 (50.1) | 1938 (47.5) | |
| FEV1 | |||
| >40% | 456 (31.9) | 1511 (37) | <0.002 |
| <40% | 8 (0.6) | 40 (1) | |
| Missing | 966 (67.6) | 2532 (62) | |
| Clinical stageb | |||
| IA | 586 (41.0) | 1657 (40.6) | 0.96 |
| IB | 319 (22.3) | 934 (22.9) | |
| IIA | 233 (16.3) | 647 (15.8) | |
| IIB | 182 (12.7) | 513 (12.6) | |
| IIIA | 110 (7.7) | 332 (8.1) | |
| Previous thoracic surgery | |||
| No | 1401 (98) | 4013 (98.3) | 0.44 |
| Yes | 29 (2) | 70 (1.7) | |
| Resection | |||
| Pneumonectomy | 118 (8.3) | 281 (6.9) | 0.099 |
| Bilobectomy | 74 (5.2) | 254 (6.2) | |
| Lobectomy | 1201 (84.4) | 3465 (84.9) | |
| Segmental resection | 37 (2.6) | 83 (2) | |
| Approach | |||
| Video-assisted thoracoscopic surgery | 1009 (70.6) | 2762 (67.6) | <0.001 |
| Thoracotomy | 379 (26.5) | 1156 (28.3) | |
| Robot-assisted thoracic surgery | 38 (2.7) | 57 (1.4) | |
| Missing | 4 (0.3) | 108 (2.6) | |
a
χ 2 test for trend.
b
TNM 7th edition.
ASA: American Society of Anesthesiologists; DLCO: diffusing capacity of the lung for carbon monoxide (preoperative); FEV1: forced expired volume in 1 s (preoperative).