Table 3. Side effects and compliance.

^ > 90% of a medication was taken

BT, high-dose esomeprazole and amoxicillin; SQ, sequential therapy; CT, concomitant therapy

Adverse events	BT group (N=130)	SQ group (N= 132)	CT group (N= 131)	p
Diarrhea	7% (9)	12.9% (17)	23.7% (31)	0.001
Abdominal pain	3.1% (4)	10.6% (14)	14.0% (19)	0.005
Metallic taste	2.3% (3)	4.5% (6)	19.8% (26)	0.0001
Nausea/Vomiting	0.8% (1)	3.8% (5)	10% (13)	0.001
Headache	3.1% (4)	3.8% (5)	8.4% (11)	0.11
Skin eruption	1.5% (2)	0.8% (1)	0.8% (1)	0.7
Asthenia	3.1% (4)	3.8% (5)	4.6% (6)	0.8
Compliance^	93.8%	98.5%	95.9%	0.16