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. 2020 Dec 24;11(1):1656–1673. doi: 10.1080/21505594.2020.1848108

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This work was authored as part of the Contributor’s official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 U.S.C. 105, no copyright protection is available for such works under U.S. Law.

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Figure 6. — Different alterations in STAT signaling between the lung and brain strains compared to the vaccine strain. Monocyte-derived macrophages infected at MOI of 2 with the three strains for 2 d were probed by western blot for: pSTAT1-Y701, STAT1 total, pSTAT5-Y694, STAT5total, SOCS3, and β-actin (n = 3 for STAT1 immunoblots and n = 4 for STAT5 and SOCS3 immunoblots). (A1), (B1), and (C1) representative blots and (A2), (B2), and (C2) are the cumulative data for the experiments. Data, mean ± SD (n ≥ 3; *p < 0.05, **p < 0.01, ***p < 0.001; ANOVA)