Figure 1.
Effects of androgen receptor knockout (ARKO) on body weight gain, feed efficiency, and digestive efficiency in male mice fed a high-fat diet (HFD). Mice were fed an HFD up to 20-weeks of age, as previously described.27 (a) Changes in body weight (%) and (b) feed efficiency (body weight gain/food intake) were determined once a week (control, n = 16; ARKO, n = 19). (c) Digestive efficiency (dried fecal weight/food intake) was determined at 6, 12, and 17 weeks (n = 11). Data were expressed as mean ± SEM, and the threshold for statistical significance was set at p < .05, *.