Figure 5.
Thi-hyd showed good tolerability in mice. (a) and (b) Eye-ball blood was collected before the sacrifice of mice. No apparent difference was observed in hematological parameters (WBC, white blood cell, 109/L; RBC, red blood cell, 109/L; PLT, platelet, 109/L) and serum biochemistry parameters (ALT, alanine aminotransferase, U/L; AST, aspartate aminotransferase, U/L; CK, creatinine kinase, U/L; CREA, creatinine, μM/L) (c) No visible pathological changes were observed in the heart, spleen, and kidney of mice by H&E staining. Scale bar, 100 μm