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Immunohistochemical staining for proliferator-activated receptor β/δ. PPAR β/δ is scantily expressed in external auditory canal skin (a–c). PPAR β/δ is expressed in the cells mainly in the parabasal and basal layers of cholesteatoma epithelium (d–f). The intensity of its expression is decreased in the granular and prickle cell layers (magnification, ×200).
