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Ligand activation of PPAR β/δ facilitates the proliferation of human cholesteatoma keratinocytes in vitro. (a, c) The effect of GW0742 (a high affinity PPAR β/δ agonist) (a) and GSK0660 (a high affinity PPAR β/δ antagonist) (c) on cell proliferation was detected by EdU assays. (b, d) Data were based on at least three independent experiments and presented as the mean ± SD; ∗p < 0.05 (vs. control group).
