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Suppressive effects of SOCS3 on LPS-induced ROS and inflammatory cytokine production accompanied by increased NRF-2 and thioredoxin expression. THP1 cells transduced with Flag or Flag-SOCS3 were analyzed for LPS-induced intracellular ROS (A), NRF-2, thioredoxin and SOCS3 levels by Western blot (B), and inflammatory cytokine production by ELISA (C).
