Table 2.
Infectivity of different HEV genotypes/subtypes in rabbits.
| Group | Genotype/subtype | Infectivity (%) | |||
|---|---|---|---|---|---|
| Acute infectiona | Chronic infectiona | Inapparent infectiona | No sign of infection | ||
| A | hHEV-3b | 0/5 (0) | 0/5 (0) | 3/5 (60) | 2/5 (40) |
| B | hHEV-4d | 5/5 (100) | 0/5 (0) | 0/5 (0) | 0/5 (0) |
| C | sHEV-4d | 4/5 (80) | 0/5 (0) | 0/5 (0) | 1/5 (20) |
| D | sHEV-4h | 0/5 (0) | 0/5 (0) | 0/5 (0) | 5/5 (100) |
| E | HEV8 | 0/5 (0) | 0/5 (0) | 1/5 (20) | 4/5 (80) |
| F | HEV-3ra | 4/5 (80) | 1/5 (20) | 0/5 (0) | 0/5 (0) |
| G | hHEV-4a | 0/2 (0) | 0/2 (0) | 0/2 (0) | 2/2 (100) |
| H | hHEV-4h | 0/2 (0) | 0/2 (0) | 0/2 (0) | 2/2 (100) |
| I | Negative control | 0/3 (0) | 0/3 (0) | 0/3 (0) | 3/3 (100) |
NA, not applicable; NT, not tested.
a
Acute infection: fecal virus shedding less than 3 months; chronic infection: fecal virus shedding over 3 months; inapparent infection: no signs of HEV infection except for seroconversion to anti-HEV antibody.