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. 2020 Oct 22;15(1):80–90. doi: 10.1002/1878-0261.12817

Fig. 5.

Fig. 5

Tumor variant allele fraction (AF) of confirmed germline variants. Distribution of observed VAF in 32 confirmed germline sequence variants. Six germline variants, all VUS, were identified in tumors at VAF < 40%, whereas all germline PVs were present in tumors at VAF > 40%.