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α-Hederin inhibits c-Myc and HIF -1α by activating expression of SIRT6. (a) A549 cells were treated with α-hederin for 24 h. Expression of SIRT6 was detected by western blot. (b) A549 cells were treated with α-hederin or SIRT6 inhibitor OSS_128167 for 24 h. Expression of c-Myc and HIF-1α was detected by western blots.
