Histological analysis of the colon obtained from the various experimental groups
Representative histological fields at two magnifications (×50 and ×200) of the various treatment groups as indicated. Vehicle, tap water-administered animal group; siTNF, animals treated with modified E. coli MDS42 strains containing psiTNF and invasive plasmids; DSS, colon specimen of the 2.5% DSS-treated animals; DSS-siTNF, animals administered 2.5% DSS and treated by modified E. coli MDS42 strains containing psiTNF and invasive plasmids.