Figure 8.

Effect of the 4 + 10 days of 2.5% DSS-induced colitis on colon length and the DAI of colitis

(A) Effect of the modified E. coli MDS42 strains containing psiTNF and invasive plasmids on colon length. The animals were administered 2.5% DSS. (B) Biological effect of modified E. coli MDS42 strains containing psiTNF and invasive plasmids were evaluated considering the DAI of 2.5% DSS-induced colitis. DSS, colon specimen of the DSS-treated animals; DSS-siTNF, animals administered DSS and treated by modified E. coli MDS42 strains containing psiTNF and invasive plasmids; DSS-pSuper, animals administered DSS and treated by modified E. coli MDS42 strains containing pSuper (empty vector) and invasive plasmids. Data represent the mean (SD). ∗p < 0.05, ∗∗p < 0.01.