Table 2.
Baseline characteristics in different ACE gene polymorphism categories (n = 934).
| Variables | Genotype DD (n-392; 42.0%) |
Genotype ID (n-321; 34.4%) |
Genotype II (n-221; 23.6%) |
p-value |
|---|---|---|---|---|
| CAD risk factors | ||||
| Age | ||||
| Mean age (years) | 53.7 ± 12.7 | 54.9 ± 12.3 | 53.6 ± 12.2 | 0.374 |
| Age < 40 years | 50 (12.8) | 35 (10.9) | 26 (11.8) | 0.748 |
| Age > 60 years | 107 (27.3) | 104 (32.4) | 85 (29.4) | 0.331 |
| Male gender | 3318 (81.7) | 273 (85) | 190 (86.0) | 0.206 |
| Hypertension | 148 (37.8) | 117 (36.4) | 71 (32.1) | 0.369 |
| Diabetes | 165 (42.09) | 129(40.18) | 89(40.27) | 0.848 |
| Smoking | 211 (53.8) | 170 (53) | 106 (48) | 0.354 |
| Dyslipidemia | 368 (93.9) | 311 (96.9) | 209 (94.9) | 0.168 |
| Blood reports: | ||||
| Hemoglobin (G/dl) | 14.0 ± 2.1 | 14.2 ± 2.2 | 13.9 ± 2.3 | 0.372 |
| Serum creatinine | 0.98 ± 0.44 | 0.99 ± 0.37 | 0.95 ± 0.27 | 0.299 |
| Total cholesterol (mg/dl) | 188.5 ± 79.2 | 185.0 ± 45.3 | 178.9 ± 40.7 | 0.175 |
| Low density lipoprotein (mg/dl) | 128.6 ± 88.4 | 125.9 ± 37.7 | 120.1 ± 37.1 | 0.283 |
| High density lipoprotein (mg/dl) | 34.1 ± 9.9 | 34.6 ± 9.6 | 34.0 ± 10.3 | 0.738 |
| 2D Echocardiography | ||||
| LVEF (%) | 44.2 ± 7.7 | 45.1 ± 7.3 | 44.4 ± 7.9 | 0.252 |
LVEF = Left ventricular ejection fraction.