Table 5.
Comparative demographic, clinical, angiographic, biochemical parameters and genotype distribution among patients who survived and expired in hospital (n = 934).
| Variables | Survival (n = 846)(%) |
In hospital death (n = 88)(%) |
p-value |
|---|---|---|---|
| Clinical parameters: | |||
| Age > 60 years (276) | 228 (27) | 48 (54.5) | <0.001 |
| Age < 40 years (111) | 107 (12.6) | 4 (4.5) | <0.001 |
| Male gender | 728 (86.1) | 53 (60.2) | <0.001 |
| Smoking | 425 (50.2) | 62(70.5) | <0.001 |
| Hypertension | 299 (35.3) | 37(42.0) | 0.243 |
| Diabetes | 331 (39.2) | 52 (59.1) | <0.001 |
| Laboratory Parameters | |||
| Random Blood Sugar > 200 mg/dl | 221 (26.1) | 43 (48.9) | <0.001 |
| Dyslipidemia | |||
| LDL-c > 100 mg/dl | 597 (70.7) | 54 (51.4) | 0.048 |
| HDL-c < 40 mg/dl in males, <50 mg/dl in females |
674 (79.7) | 79 (89.8) | 0.012 |
| LV Ejection Fraction < 35%) | 30 (3.5) | 33 (37.5) | <0.001 |
| Angiographic Findings: | |||
| Single vessel disease | 310 (62.1) | 8 (57.1) | 0.330 |
| Double vessel disease | 119 (23.8) | 2 (14.3) | |
| Triple vessel disease | 63 (12.6) | 4 (28.6) | |
| Left main coronary artery | 7 (1.4) | 0 (0) | |
| Flowing culprit artery | 429(86.0) | 8 (57.0) | 0.014 |
| Occluded culprit artery | 70 (14.0) | 6 (43.0) | |
| ACE Genotypes | |||
| Genotype DD | 355 (42) | 37 (42) | 0.453 |
| Genotype ID | 295 (34.9) | 26 (29.5) | |
| Genotype II | 196 (23.2) | 25 (28.4) | |
| ACE Activity | 234.2 ± 183.3 | 217.6 ± 158.4 | 0.482 |
| Median ACE Activity (≤194.4.U/L) | 274 (49.9) | 35 (53) | 0.364 |
| Median ACE Activity (>194.4.U/L) | 275 (50.1) | 31 (47) | |
| Mean ACE Activity (≤232.4.U/L) | 333 (60.7) | 43 (65.2) | 0.285 |
| Mean ACE Activity (>232.4.U/L) | 216 (39.3) | 23 (34.8) |
LDL = low density lipoprotein; HDL = high density lipoprotein.