Table 3.

Cox regression

			Univariate analysis			Multivariate analysis
		n	HR1	95% CI	p	HR1	95% CI	p
Sex	Male	51	1.0
	Female	37	1.0	0.6–1.9	0.901
Localization	Rectum	37	1.0
	Colon	51	1.0	0.5–1.8	0.953
T-category	pT1	13	1.0
	pT2	8	2.6	0.4–18.7	0.336
	pT3	37	4.0	0.9–17.0	0.064
	pT4	19	9.4	2.1–41.4	0.003
	ypT3	5	8.0	1.3–48.6	0.024
	ypT4	3	5.5	0.5–60.8	0.166
N-category	pN0	44	1.0
	pN1	13	2.3	1.0–5.4	0.044
	pN2	18	2.6	1.3–5.8	0.011
	ypN0	3	0.9	0.1–6.6	0.890
	ypN1	4	2.3	0.5–10.5	0.262
	ypN2	2	18.4	1.9–172.9	0.011
M-category	cM0	66	1.0
	cM1	21	7.7	3.7–15.7	< 0.001
Inflammatory bowel disease	Ulcerative colitis	68	1.0			1.0
	Crohn’s colitis	20	2.3	1.2–4.5	0.011	2.3	1.0–5.6	0.061
Stage (UICC)	Stage I	19				1.0
	Stage II	23	2.4	0.6–8.7	0.200	1.8	0.5–7.0	0.407
	Stage III	17	2.8	0.7–10.3	0.124	2.4	0.6–9.1	0.216
	Stage IV	17	39.7	9.7–161.2	< 0.001	22.3	3.3–151.6	0.002
	Stage yII	2	5.1	0.5–49.8	0.160	5.5	0.6–54.2	0.145
	Stage yIII	2	9.3	0.9–92.7	0.057	9.4	0.9–94.7	0.057
	Stage yIV	4	11.4	1.8–72.4	0.010	5.7	0.3–88.6	0.216
R classification	R0	65	1.0			1.0
	R1	2	18.0	2.1–156.1	0.009	14.4	0.5–385.7	0.113
	R2	14	14.2	6.1–32.9	< 0.001	2.3	0.6–9.4	0.241
Histological type	Adenocarcinoma	67	1.0			1.0
	Non-adenocarcinoma	18	2.0	1.0–4.0	0.042	1.2	0.5–3.0	0.681

¹Hazard ratio