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. 2021 Jan 4;12:28. doi: 10.1038/s41467-020-20194-0

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© The Author(s) 2021

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Fig. 1 — a The SOX family is comprised of 20 members and are grouped based on domain organization. A representative from each SOX group is shown. b Each SOX family member contains a highly conserved HMG domain (in green/pink), with NLSs positioned within the extremities of the HMG domain. The residues within SOX2 that form hydrogen bonds or salt bridges with IMPα3 in our crystal structure are highlighted (in pink).