Fig. 2. DOPAL inhibits Aβ40 fibril formation in a dose-dependent manner.

a Aggregation kinetics of Aβ40 in NaP pH 6.9, 0.2 mM EDTA in the absence (empty circles) and presence (filled circles) of increasing molar equivalents of DOPAL (represented in different colours). b Normalised to control (absence of DOPAL) half-time (t_1/2) of aggregation (points) and end point fluorescence intensities (asterisks) as derived from the data in a. Throughout, error bars represent means ± SEM of three replicates.