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. 2021 Jan 4;12:22. doi: 10.1038/s41467-020-20294-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a UMAP 2D projection of the Celligner-alignment with breast, kidney, hematopoietic, and skin samples highlighted in red. b Luminal and basal breast cancer subtypes cluster together for cell lines and tumors (n = 56 cell lines, n = 1,099 tumors). c Leukemia tumor and cell lines co-cluster in the aligned data by subtype (n = 197 cell lines, n = 1,218 tumors). d Myeloma cell lines cluster near the hematopoietic samples, but distinct from the tumors (n = 96 cell lines, n = 109 tumors). e Skin cancer melanocytic, transitory, neural crest-like, and undifferentiated subtypes align between cell lines and tumors (n = 63 cell lines, n = 459 tumors). f Kidney chromophobe tumor samples do not cluster with any cell lines (n = 34 cell lines, n = 1019 tumors).