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. 2021 Jan 4;4:13. doi: 10.1038/s42003-020-01551-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Illustration of the unique TCR clones (unique) in the blood (black) and the skin (gray) and the shared TCRs found both in the blood and in the skin (shared, red) of the same individual. In this example, shared/unique is 10/30 in the skin and 10/110 in the blood. b Frequency of shared clones per unique clones between the blood and the skin. The two-tailed Spearman rank correlation coefficients were performed. NS not significant, **p < 0.01. c The relative sizes of the unique clone pools in the skin and the blood were estimated by the average numbers of the shared clones and the % shared/unique in the skin and blood of the 3 age groups. d Common clones in the different participants of each age group. NS not significant, **p < 0.01.