Table 2.

PAM50 intrinsic subtypes distribution within HR-positive and TN tumors according to HER2 status.

HR-positive	HER2 0		HER2-low		Overall		pa
	N	%	N	%	N	%
PAM50 subtypes
Luminal A	187	51.8	457	58.9	644	56.6	<0.001
Luminal B	126	34.9	259	33.4	385	33.9
HER2-enriched	12	3.3	23	3.0	35	3.1
Basal-like	29	8.0	15	1.9	44	3.9
Normal-like	7	1.9	22	2.8	29	2.6
Total	361	31.8	776	100.0	1,137	100.0
TNBC
PAM50 subtypes
Luminal A	5	1.6	2	1.6	7	1.6	0.438
Luminal B	1	0.3	0	0.0	1	0.2
HER2-enriched	28	9.0	9	7.1	37	8.5
Basal-like	265	85.2	105	83.3	370	84.7
Normal-like	12	3.9	10	7.9	22	5.0
Total	311	71.2	126	100.0	437	100.0

HR hormone receptor, TNBC triple-negative breast cancer.

^aChi-square test for differences in proportions.